Review of Tolvaptan’s Pharmacokinetic and Pharmacodynamic Properties and Drug Interactions
نویسندگان
چکیده
منابع مشابه
Review of Tolvaptan’s Pharmacokinetic and Pharmacodynamic Properties and Drug Interactions
Tolvaptan is an arginine vasopressin (AVP) antagonist that acts to increase excretion of free water (aquaresis) in patients without introducing electrolyte abnormalities or worsening renal function. It works via blockade of vasopressin-2 receptors at the renal collecting duct. Since the approval of tolvaptan for the treatment of hypervolemic and euvolemic hyponatremia in 2009, new studies have ...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2014
ISSN: 2077-0383
DOI: 10.3390/jcm3041276